{"code":"C96515","name":"Single Cell Gel Electrophoresis","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":false,"active":true,"synonyms":[{"name":"COMET","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Comet Assay","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Single Cell Gel Electrophoresis","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Single Cell Gel Electrophoresis","type":"Preferred_Name","typeCode":"P108"}],"definitions":[{"definition":"A rapid, simple, visual and sensitive technique for measuring DNA breakage in individual mammalian cells in response to a test agent. A cell is immobilized in agarose and made permeable and the broken DNA migrates out under the influence of the electric field. A damaged cell has the appearance of a comet with a brightly fluorescent cell body and a tail whose length and fluorescence intensity are related to the number of DNA-strand breaks induced by the test agent.","code":"P97","type":"DEFINITION","source":"NCI"}],"properties":[{"code":"P106","type":"Semantic_Type","value":"Laboratory Procedure"},{"code":"P207","type":"UMLS_CUI","value":"C0751980"}]}