{"code":"C95408","name":"Anticardiolipin Antibody","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":false,"active":true,"synonyms":[{"name":"Anticardiolipin Antibody","termType":"DN","type":"FULL_SYN","typeCode":"P90","source":"CTRP"},{"name":"Anticardiolipin Antibody","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"ACA","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NICHD"},{"name":"aCL","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NICHD"},{"name":"Anticardiolipin Antibody","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NICHD"},{"name":"Anticardiolipin Antibody","type":"Display_Name","typeCode":"P107"},{"name":"Anticardiolipin Antibody","type":"Preferred_Name","typeCode":"P108"}],"definitions":[{"definition":"An antiphospholipid autoantibody that reacts with cardiolipin. It can be associated with antiphospholipid antibody syndrome and system lupus erythematosus.","code":"P325","type":"ALT_DEFINITION","source":"NICHD"},{"definition":"An autoantibody that reacts with cardiolipin. Different immunoglobulin subclasses and isotypes are associated with different diseases and conditions. Some anticardiolipin antibodies prolong phospholipid dependent clotting while others are associated with spontaneous abortion.","code":"P97","type":"DEFINITION","source":"NCI"}],"properties":[{"code":"P322","type":"Contributing_Source","value":"CTRP"},{"code":"P322","type":"Contributing_Source","value":"NICHD"},{"code":"P106","type":"Semantic_Type","value":"Amino Acid, Peptide, or Protein"},{"code":"P106","type":"Semantic_Type","value":"Immunologic Factor"},{"code":"P207","type":"UMLS_CUI","value":"C0162596"}]}