{"code":"C88359","name":"Cystatin-C","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":true,"active":true,"synonyms":[{"name":"Cystatin-C","termType":"DN","type":"FULL_SYN","typeCode":"P90","source":"CTRP"},{"name":"Cystatin C","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Cystatin-3","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Cystatin-C","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Gamma-Trace","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Neuroendocrine Basic Polypeptide","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Post-Gamma-Globulin","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Cystatin-C","type":"Display_Name","typeCode":"P107"},{"name":"Cystatin-C","type":"Preferred_Name","typeCode":"P108"}],"definitions":[{"definition":"Cystatin-C (146 aa, ~16 kDa) is encoded by the human CST3 gene. This protein is involved in the inhibition of cysteine proteinases.","code":"P97","type":"DEFINITION","source":"NCI"}],"properties":[{"code":"P322","type":"Contributing_Source","value":"CTRP"},{"code":"P98","type":"DesignNote","value":"Cystatin-C found in cerebrospinal fluid may be a marker for the diagnosis of Creutzfeldt-Jakob disease. (UniProt)"},{"code":"P98","type":"DesignNote","value":"Serum cystatin-C is a marker for the assessment of renal function or glomerular filtration rate."},{"type":"Logical_Definition","value":"true"},{"code":"P100","type":"OMIM_Number","value":"604312"},{"code":"P106","type":"Semantic_Type","value":"Amino Acid, Peptide, or Protein"},{"code":"P93","type":"Swiss_Prot","value":"P01034"},{"code":"P207","type":"UMLS_CUI","value":"C1453113"}]}