{"code":"C524","name":"Glycine","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":true,"active":true,"synonyms":[{"name":"Aminoethanoic acid","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"CRCH"},{"name":"Gly","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"CRCH"},{"name":"Glycine","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"CRCH"},{"name":"Glycine","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"DCP","code":"00317"},{"name":"GLYCINE","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"DTP","code":"NSC0025936"},{"name":"GLYCINE","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"FDA","code":"TE7660XO1C","subSource":"UNII"},{"name":"Glycine","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Glycine","type":"Preferred_Name","typeCode":"P108"}],"definitions":[{"definition":"A non-essential, non-polar, non-optical, glucogenic amino acid. Glycine, an inhibitory neurotransmitter in the CNS, triggers chloride ion influx via ionotropic receptors, thereby creating an inhibitory post-synaptic potential. In contrast, this agent also acts as a co-agonist, along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Glycine is an important component and precursor for many macromolecules in the cells.","code":"P97","type":"DEFINITION","source":"NCI"},{"definition":"Amino acid with side chain -H.","code":"P325","type":"ALT_DEFINITION","source":"CRCH"}],"properties":[{"code":"P210","type":"CAS_Registry","value":"56-40-6"},{"code":"P368","type":"CHEBI_ID","value":"CHEBI:15428"},{"code":"P350","type":"Chemical_Formula","value":"C2H5NO2"},{"code":"P322","type":"Contributing_Source","value":"CRCH"},{"code":"P322","type":"Contributing_Source","value":"FDA"},{"code":"P319","type":"FDA_UNII_Code","value":"TE7660XO1C"},{"code":"P366","type":"Legacy Concept Name","value":"Glycine"},{"code":"P399","type":"NCI_Drug_Dictionary_ID","value":"41347"},{"code":"P175","type":"NSC Number","value":"25936"},{"code":"P330","type":"PDQ_Closed_Trial_Search_ID","value":"41347"},{"code":"P329","type":"PDQ_Open_Trial_Search_ID","value":"41347"},{"code":"P106","type":"Semantic_Type","value":"Amino Acid, Peptide, or Protein"},{"code":"P207","type":"UMLS_CUI","value":"C0017890"}]}