{"code":"C41395","name":"Diagnostic Specificity","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":true,"active":true,"synonyms":[{"name":"specificity (medical test)","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"CDISC-GLOSS"},{"name":"specificity (medical test)","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"MRCT-Ctr"},{"name":"specificity","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI-GLOSS","code":"CDR0000322884"},{"name":"Diagnostic Specificity","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Specificity","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Specificity of Diagnostic Test","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Diagnostic Specificity","type":"Preferred_Name","typeCode":"P108"}],"definitions":[{"definition":"How well a medical test can accurately identify people who do not have a disease or trait. (https://mrctcenter.org/glossaryterm/specificity-medical-test/)","code":"P325","type":"ALT_DEFINITION","source":"MRCT-Ctr"},{"definition":"The frequency with which a test yields a true negative result among individuals who do not have the disease or the gene mutation in question. A test with high specificity has a low false-positive rate and thus does a good job of correctly classifying unaffected individuals.","code":"P325","type":"ALT_DEFINITION","source":"NCI-GLOSS"},{"definition":"The probability that a test will produce a true negative result when used on non-effected subjects as compared to a reference or \"gold standard\". The specificity of a test can be determined by calculating: number of true negative results divided by the sum of true negative results plus number of false positive results.","code":"P97","type":"DEFINITION","source":"NCI"},{"definition":"The proportion of negative tests out of all tests for subjects who do not have a disease or condition (true-negative rate). NOTE: Specificity represents the likelihood that a subject without the disease or other condition will have a negative test result. [After Diagnostic Testing Accuracy: Sensitivity, Specificity, Jacob Shreffler; Martin R. Huecker, Predictive Values and Likelihood Ratios, StatPearls Publishing, 2024 Jan; After Understanding Medical Tests and Test Results in Merck Manuals, Brian Mandell at Case Western University]","code":"P325","type":"ALT_DEFINITION","source":"CDISC-GLOSS"}],"properties":[{"code":"P322","type":"Contributing_Source","value":"CDISC-GLOSS"},{"code":"P322","type":"Contributing_Source","value":"MRCT-Ctr"},{"code":"P366","type":"Legacy Concept Name","value":"Diagnostic_Specificity"},{"code":"P106","type":"Semantic_Type","value":"Quantitative Concept"},{"code":"P207","type":"UMLS_CUI","value":"C1511884"}]}