{"code":"C41027","name":"Parathyroid Hormone","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":true,"active":true,"synonyms":[{"name":"Parathyroid Hormone","termType":"DN","type":"FULL_SYN","typeCode":"P90","source":"CTRP"},{"name":"parathormone","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI-GLOSS","code":"CDR0000403137"},{"name":"parathyrin","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI-GLOSS","code":"CDR0000403138"},{"name":"parathyroid hormone","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI-GLOSS","code":"CDR0000044339"},{"name":"Parathormone","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Parathyrin","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Parathyroid Hormone","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Parathyroid Hormone 1","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Prepro-PTH","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Preproparathyroid Hormone","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"PTH","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Parathyroid Hormone","type":"Display_Name","typeCode":"P107"},{"name":"Parathyroid Hormone","type":"Preferred_Name","typeCode":"P108"}],"definitions":[{"definition":"A substance made by the parathyroid gland that helps the body store and use calcium. A higher-than-normal amount of parathormone causes high levels of calcium in the blood and may be a sign of disease.","code":"P325","type":"ALT_DEFINITION","source":"NCI-GLOSS"},{"definition":"Parathyroid hormone (115 aa, ~13 kDa) is encoded by the human PTH gene. This protein is involved in the modulation of calcium ion and phosphate concentration in the blood.","code":"P97","type":"DEFINITION","source":"NCI"}],"properties":[{"code":"P322","type":"Contributing_Source","value":"CTRP"},{"code":"P98","type":"DesignNote","value":"Parathyroid hormone is cleaved by prohormone convertases at residue 31 releasing an 84 amino acid active peptide. (UniProt)"},{"code":"P366","type":"Legacy Concept Name","value":"Parathyroid_Hormone"},{"code":"P208","type":"NCI_META_CUI","value":"CL938165"},{"code":"P100","type":"OMIM_Number","value":"168450"},{"code":"P106","type":"Semantic_Type","value":"Amino Acid, Peptide, or Protein"},{"code":"P106","type":"Semantic_Type","value":"Hormone"},{"code":"P93","type":"Swiss_Prot","value":"P01270"}]}