{"code":"C40960","name":"Chromogenic In Situ Hybridization","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":false,"active":true,"synonyms":[{"name":"Chromogenic in Situ Hybridization","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"CDISC"},{"name":"CISH","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"CDISC"},{"name":"Chromogenic In Situ Hybridization","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Chromogenic in situ Hybridization","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"CISH","termType":"AB","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Chromogenic In Situ Hybridization","type":"Preferred_Name","typeCode":"P108"}],"definitions":[{"definition":"A laboratory procedure that combines the sequence-specific detection aspects of FISH with the simple detection methods of immunohistochemistry. Briefly, sequence-specific probes are hybridized to cells fixed on slides and the sequestered probe is visualized by a peroxidase reaction. It has the advantage of being a less costly assay that does not require fluorescence microscopy with results that are stable over time.","code":"P97","type":"DEFINITION","source":"NCI"},{"definition":"A laboratory procedure that combines the sequence-specific detection aspects of FISH with the simple detection methods of immunohistochemistry. Briefly, sequence-specific probes are hybridized to cells fixed on slides and the sequestered probe is visualized by a peroxidase reaction. It has the advantage of being a less costly assay that does not require fluorescence microscopy with results that are stable over time.","code":"P325","type":"ALT_DEFINITION","source":"CDISC"}],"properties":[{"code":"P322","type":"Contributing_Source","value":"CDISC"},{"code":"P366","type":"Legacy Concept Name","value":"Chromogenic_in_situ_Hybridization"},{"code":"P106","type":"Semantic_Type","value":"Molecular Biology Research Technique"},{"code":"P207","type":"UMLS_CUI","value":"C1516514"}]}