{"code":"C341","name":"Carbamazepine","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":true,"active":true,"synonyms":[{"name":"Tegretol","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"DTP","code":"NSC0169864"},{"name":"CARBAMAZEPINE","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"FDA","code":"33CM23913M","subSource":"UNII"},{"name":"5H-Dibenz(b,f)azepine-5-carboxamide","termType":"SN","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Carbamazepine","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Epitol","termType":"BR","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Tegretol","termType":"BR","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Carbamazepine","type":"Preferred_Name","typeCode":"P108"}],"definitions":[{"definition":"A tricyclic compound chemically related to tricyclic antidepressants (TCA) with anticonvulsant and analgesic properties. Carbamazepine exerts its anticonvulsant activity by reducing polysynaptic responses and blocking post-tetanic potentiation. Its analgesic activity is not understood; however, carbamazepine is commonly used to treat pain associated with trigeminal neuralgia.","code":"P97","type":"DEFINITION","source":"NCI"}],"properties":[{"code":"P302","type":"Accepted_Therapeutic_Use_For","value":"Epilepsy"},{"code":"P210","type":"CAS_Registry","value":"298-46-4"},{"code":"P368","type":"CHEBI_ID","value":"CHEBI:3387"},{"code":"P350","type":"Chemical_Formula","value":"C15H12N2O"},{"code":"P322","type":"Contributing_Source","value":"FDA"},{"code":"P319","type":"FDA_UNII_Code","value":"33CM23913M"},{"code":"P366","type":"Legacy Concept Name","value":"Carbamazepine"},{"code":"P399","type":"NCI_Drug_Dictionary_ID","value":"42418"},{"code":"P175","type":"NSC Number","value":"169864"},{"code":"P330","type":"PDQ_Closed_Trial_Search_ID","value":"42418"},{"code":"P329","type":"PDQ_Open_Trial_Search_ID","value":"42418"},{"code":"P106","type":"Semantic_Type","value":"Organic Chemical"},{"code":"P106","type":"Semantic_Type","value":"Pharmacologic Substance"},{"code":"P207","type":"UMLS_CUI","value":"C0006949"}]}