{"code":"C30111","name":"Tumor Necrosis Factor Receptor Superfamily Member 11B","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":true,"active":true,"synonyms":[{"name":"Tumor Necrosis Factor Receptor Superfamily Member 11B","termType":"DN","type":"FULL_SYN","typeCode":"P90","source":"CTRP"},{"name":"Osteoclastogenesis Inhibitory Factor","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Osteoprotegerin","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"TNFRSF11B","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Tumor Necrosis Factor Receptor Superfamily Member 11B","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Tumor Necrosis Factor Receptor Superfamily Member 11B","type":"Display_Name","typeCode":"P107"},{"name":"Tumor Necrosis Factor Receptor Superfamily Member 11B","type":"Preferred_Name","typeCode":"P108"}],"definitions":[{"definition":"Tumor necrosis factor receptor superfamily member 11B (401 aa, ~46 kDa) is encoded by the human TNFRSF11B gene. This protein plays a role in the negative regulation of both osteoblast differentiation and bone resorption.","code":"P97","type":"DEFINITION","source":"NCI"}],"properties":[{"code":"P322","type":"Contributing_Source","value":"CTRP"},{"code":"P366","type":"Legacy Concept Name","value":"Osteoprotegerin"},{"type":"Logical_Definition","value":"true"},{"code":"P100","type":"OMIM_Number","value":"602643"},{"code":"P106","type":"Semantic_Type","value":"Amino Acid, Peptide, or Protein"},{"code":"P106","type":"Semantic_Type","value":"Receptor"},{"code":"P93","type":"Swiss_Prot","value":"O00300"},{"code":"P207","type":"UMLS_CUI","value":"C1308614"}]}