{"code":"C28418","name":"Somatostatin","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":true,"active":true,"synonyms":[{"name":"Somatostatin","termType":"DN","type":"FULL_SYN","typeCode":"P90","source":"CTRP"},{"name":"GHIH","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Growth Hormone Release Inhibiting Factor","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Growth Hormone Release-Inhibiting Factor","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Growth Hormone-Inhibiting Hormone","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Panhibin","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Prepro-Somatostatin","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Somatostatin","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Somatotropin Release Inhibiting Factors","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"SST","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Somatostatin","type":"Display_Name","typeCode":"P107"},{"name":"Somatostatin","type":"Preferred_Name","typeCode":"P108"}],"definitions":[{"definition":"Somatostatin (116 aa, ~13 kDa) is encoded by the human SST gene. This protein plays a role in the downregulation of somatotropin release.","code":"P97","type":"DEFINITION","source":"NCI"}],"properties":[{"code":"P322","type":"Contributing_Source","value":"CTRP"},{"code":"P98","type":"DesignNote","value":"Somatostatin is cleaved into one of two peptides comprised of either amino acid residues 89-116, which is called somatostatin-28, or residues 103-116, which is called somatostatin-14. C-terminal amidation yields neuronostatin. (UniProt)"},{"code":"P366","type":"Legacy Concept Name","value":"Somatostatin"},{"type":"Logical_Definition","value":"true"},{"code":"P100","type":"OMIM_Number","value":"182450"},{"code":"P106","type":"Semantic_Type","value":"Amino Acid, Peptide, or Protein"},{"code":"P106","type":"Semantic_Type","value":"Hormone"},{"code":"P93","type":"Swiss_Prot","value":"P61278"},{"code":"P207","type":"UMLS_CUI","value":"C0037659"}]}