{"code":"C25159","name":"Carcinoembryonic Antigen","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":true,"active":true,"synonyms":[{"name":"Carcinoembryonic Antigen","termType":"DN","type":"FULL_SYN","typeCode":"P90","source":"CTRP"},{"name":"carcinoembryonic antigen","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI-GLOSS","code":"CDR0000357558"},{"name":"CEA","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI-GLOSS","code":"CDR0000046474"},{"name":"Carcinoembryonic Antigen","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Carcinoembryonic Antigen Family Protein","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"CD66 Antigen Family Protein","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"CD66 Family Protein","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"CEA","termType":"AB","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"CEA Family Protein","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Carcinoembryonic Antigen","type":"Display_Name","typeCode":"P107"},{"name":"Carcinoembryonic Antigen","type":"Preferred_Name","typeCode":"P108"}],"definitions":[{"definition":"A cancer-specific antigen associated with both tumors and the developing fetus. The main use of this antigen is as a tumor marker, especially with respect to intestinal cancers. Production of the antigen ceases shortly before birth, but may reappear in people who develop certain types of cancer.","code":"P97","type":"DEFINITION","source":"NCI"},{"definition":"A substance that is sometimes found in an increased amount in the blood of people who have certain cancers, other diseases, or who smoke. It is used as a tumor marker for colorectal cancer.","code":"P325","type":"ALT_DEFINITION","source":"NCI-GLOSS"}],"properties":[{"code":"P322","type":"Contributing_Source","value":"CTRP"},{"code":"P98","type":"DesignNote","value":"Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. (OMIM)"},{"code":"P98","type":"DesignNote","value":"The term carcinoembryonic antigen (CEA) may refer to the CEA protein family but it is sometimes used to refer to CEACAM5 (carcinoembryonic antigen-related cell adhesion molecule 5) alone."},{"code":"P366","type":"Legacy Concept Name","value":"Carcinoembryonic_Antigen"},{"code":"P106","type":"Semantic_Type","value":"Amino Acid, Peptide, or Protein"},{"code":"P207","type":"UMLS_CUI","value":"C0007082"}]}