{"code":"C2304","name":"Thyroglobulin","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":true,"active":true,"synonyms":[{"name":"Tg","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"CDISC"},{"name":"THYROGLOBULIN","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"CDISC"},{"name":"Thyroid Thyroglobulin","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"CDISC"},{"name":"Thyroglobulin","termType":"DN","type":"FULL_SYN","typeCode":"P90","source":"CTRP"},{"name":"thyroglobulin","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI-GLOSS","code":"CDR0000044556"},{"name":"TG","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Thyroglobulin","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Thyroglobulin","type":"Display_Name","typeCode":"P107"},{"name":"Thyroglobulin","type":"Preferred_Name","typeCode":"P108"}],"definitions":[{"definition":"An antigen encoded by the TG gene that regulates thyroid hormone synthesis. It can be considered as an autoantigen and is commonly associated with autoimmune thyroid diseases.","code":"P325","type":"ALT_DEFINITION","source":"CDISC"},{"definition":"The form that thyroid hormone takes when stored in the cells of the thyroid. If the thyroid has been removed, thyroglobulin should not show up on a blood test. Doctors measure thyroglobulin level in blood to detect thyroid cancer cells that remain in the body after treatment.","code":"P325","type":"ALT_DEFINITION","source":"NCI-GLOSS"},{"definition":"Thyroglobulin (2768 aa, ~305 kDa) is encoded by the human TG gene. This protein is involved in thyroid hormone synthesis.","code":"P97","type":"DEFINITION","source":"NCI"}],"properties":[{"code":"P322","type":"Contributing_Source","value":"CDISC"},{"code":"P322","type":"Contributing_Source","value":"CTRP"},{"code":"P98","type":"DesignNote","value":"Thyroglobulin is the precursor for both the free and iodinated forms of thyroxine (T4) and triiodothyronine (T3)."},{"code":"P366","type":"Legacy Concept Name","value":"Thyroglobulin"},{"code":"P100","type":"OMIM_Number","value":"188450"},{"code":"P106","type":"Semantic_Type","value":"Amino Acid, Peptide, or Protein"},{"code":"P106","type":"Semantic_Type","value":"Hormone"},{"code":"P93","type":"Swiss_Prot","value":"P01266"},{"code":"P207","type":"UMLS_CUI","value":"C0040123"}]}