{"code":"C2268","name":"Glucagon","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":true,"active":true,"synonyms":[{"name":"Glucagon","termType":"DN","type":"FULL_SYN","typeCode":"P90","source":"CTRP"},{"name":"glucagon","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI-GLOSS","code":"CDR0000270860"},{"name":"GCG","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Glucagon","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"HG Factor","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"HG-Factor","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Hyperglycemic Glycogenolytic Factor","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Hyperglycemic-Glycogenolytic Factor","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Glucagon","type":"Display_Name","typeCode":"P107"},{"name":"Glucagon","type":"Preferred_Name","typeCode":"P108"}],"definitions":[{"definition":"A hormone produced by the pancreas that increases the level of glucose (sugar) in the blood.","code":"P325","type":"ALT_DEFINITION","source":"NCI-GLOSS"},{"definition":"Glucagon (29 aa, ~3 kDa) is encoded by the human GCG gene. This protein plays a role in the regulation of blood sugar levels through the stimulation of hepatic glycogenolysis and gluconeogenesis.","code":"P97","type":"DEFINITION","source":"NCI"}],"properties":[{"code":"P322","type":"Contributing_Source","value":"CTRP"},{"code":"P98","type":"DesignNote","value":"Glucagon is comprised of amino acids 53-81 of the full length proglucagon precursor protein. (UniProt)"},{"code":"P366","type":"Legacy Concept Name","value":"Glucagon"},{"type":"Logical_Definition","value":"true"},{"code":"P100","type":"OMIM_Number","value":"138030"},{"code":"P106","type":"Semantic_Type","value":"Amino Acid, Peptide, or Protein"},{"code":"P106","type":"Semantic_Type","value":"Hormone"},{"code":"P93","type":"Swiss_Prot","value":"P01275"},{"code":"P207","type":"UMLS_CUI","value":"C0017687"}]}