{"code":"C2190","name":"Alcohol","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":true,"active":true,"synonyms":[{"name":"Alcohol","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"caDSR"},{"name":"Alcohol","termType":"DN","type":"FULL_SYN","typeCode":"P90","source":"CTRP"},{"name":"Ethanol","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"DCP","code":"00164"},{"name":"Absolute ethanol","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"DTP","code":"NSC0085228"},{"name":"Alcohol","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"DTP","code":"NSC0085228"},{"name":"ETHANOL","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"DTP","code":"NSC0085228"},{"name":"ALCOHOL","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"FDA","code":"3K9958V90M","subSource":"UNII"},{"name":"alcohol","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI-GLOSS","code":"CDR0000463134"},{"name":"Absolute Ethanol","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Alcohol","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Dehydrated Alcohol","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Dehydrated Ethanol","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Ethanol","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Ethyl Alcohol","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Methylcarbinol","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Alcohol","type":"Display_Name","typeCode":"P107"},{"name":"Alcohol","type":"Preferred_Name","typeCode":"P108"}],"definitions":[{"definition":"A chemical substance found in beer, wine, and liquor, and some medicines, mouthwashes, household products, and essential oils (scented liquid taken from plants). Alcohol contains a carbon atom attached to a hydroxyl group (a molecule made of an oxygen atom and a hydrogen atom).","code":"P325","type":"ALT_DEFINITION","source":"NCI-GLOSS"},{"definition":"A volatile liquid prepared by fermentation of certain carbohydrates. Alcohol acts as a central nervous system (CNS) depressant, a diuretic, and a disinfectant. Although the exact mechanism of CNS depression is unknown, alcohol may act by inhibiting the opening of calcium channels, mediated by the binding of the inhibitory neurotransmitter gamma-amino butyric acid (GABA) to GABA-A receptors, or through inhibitory actions at N-methyl-D-aspartate (NMDA)-type glutamate receptors. Alcohol inhibits the production of antidiuretic hormone, thereby producing diuresis that may lead to dehydration. This agent kills organisms by denaturing their proteins.","code":"P97","type":"DEFINITION","source":"NCI"}],"properties":[{"code":"P210","type":"CAS_Registry","value":"64-17-5"},{"code":"P368","type":"CHEBI_ID","value":"CHEBI:16236"},{"code":"P350","type":"Chemical_Formula","value":"C2H6O"},{"code":"P322","type":"Contributing_Source","value":"CTRP"},{"code":"P322","type":"Contributing_Source","value":"FDA"},{"code":"P319","type":"FDA_UNII_Code","value":"3K9958V90M"},{"code":"P366","type":"Legacy Concept Name","value":"Alcohol"},{"code":"P399","type":"NCI_Drug_Dictionary_ID","value":"446576"},{"code":"P175","type":"NSC Number","value":"85228"},{"code":"P330","type":"PDQ_Closed_Trial_Search_ID","value":"446576"},{"code":"P329","type":"PDQ_Open_Trial_Search_ID","value":"446576"},{"code":"P106","type":"Semantic_Type","value":"Organic Chemical"},{"code":"P106","type":"Semantic_Type","value":"Pharmacologic Substance"},{"code":"P207","type":"UMLS_CUI","value":"C0001962"}]}