{"code":"C20509","name":"Interleukin-5","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":true,"active":true,"synonyms":[{"name":"Interleukin-5","termType":"DN","type":"FULL_SYN","typeCode":"P90","source":"CTRP"},{"name":"IL-5","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI-GLOSS","code":"CDR0000682071"},{"name":"interleukin-5","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI-GLOSS","code":"CDR0000557292"},{"name":"B Cell Differentiation Factor I","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"B-Cell Differentiation Factor I","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"B-Cell Growth Factor-II","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"BCGF-II","termType":"AB","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"EDF","termType":"AB","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Eo-CSF","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Eosinophil Differentiation Factor","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"IL-5","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"IL5","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Interleukin 5","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Interleukin 5 Precursor","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Interleukin-5","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"T-Cell Replacing Factor","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"TRF","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Interleukin-5","type":"Display_Name","typeCode":"P107"},{"name":"Interleukin-5","type":"Preferred_Name","typeCode":"P108"}],"definitions":[{"definition":"Interleukin-5 (134 aa, ~15 kDa) is encoded by the human IL5 gene. This protein plays a role in the growth and differentiation of both B-cells and eosinophils.","code":"P97","type":"DEFINITION","source":"NCI"},{"definition":"One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. IL-5 is made mainly by some T lymphocytes. It causes B lymphocytes to make more antibodies and increases the number of eosinophils. IL-5 made in the laboratory is used as a biological response modifier to boost the immune system in cancer therapy. It is a type of cytokine.","code":"P325","type":"ALT_DEFINITION","source":"NCI-GLOSS"}],"properties":[{"code":"P322","type":"Contributing_Source","value":"CTRP"},{"code":"P366","type":"Legacy Concept Name","value":"Interleukin-5"},{"type":"Logical_Definition","value":"true"},{"code":"P100","type":"OMIM_Number","value":"147850"},{"code":"P106","type":"Semantic_Type","value":"Amino Acid, Peptide, or Protein"},{"code":"P106","type":"Semantic_Type","value":"Immunologic Factor"},{"code":"P93","type":"Swiss_Prot","value":"P05113"},{"code":"P207","type":"UMLS_CUI","value":"C0021759"}]}