{"code":"C18091","name":"Gel Electrophoresis","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":false,"active":true,"synonyms":[{"name":"GEL ELECTROPHORESIS","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"CDISC"},{"name":"Gel Electrophoresis","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Gel Electrophoresis","type":"Preferred_Name","typeCode":"P108"},{"name":"Gel Electropheresis","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"PCDC","subSource":"AML"}],"definitions":[{"definition":"A method of separating large molecules (such as DNA fragments or proteins) from a mixture of similar molecules by electrophoretic filtration through a gelatinous matrix.","code":"P325","type":"ALT_DEFINITION","source":"CDISC"},{"definition":"Gel electrophoresis is a method of separating large molecules (such as DNA fragments or proteins) from a mixture of similar molecules by electrophoretic filtration through a gelatinous matrix.  Subject to an electric field, each molecule in the sample mixture migrates through the matrix at a different rate, depending mainly on electrical charge and size, resulting in spatial separation within the matrix of each molecular species in the sample mixture.  Agarose and acrylamide in a cylindrical tube or slab gel are commonly used media for electrophoresis of proteins and nucleic acids.","code":"P97","type":"DEFINITION","source":"NCI"}],"properties":[{"code":"P322","type":"Contributing_Source","value":"CDISC"},{"code":"P322","type":"Contributing_Source","value":"PCDC"},{"code":"P366","type":"Legacy Concept Name","value":"Gel_Electrophoresis"},{"code":"P106","type":"Semantic_Type","value":"Molecular Biology Research Technique"},{"code":"P207","type":"UMLS_CUI","value":"C0596607"}]}