{"code":"C172555","name":"Plaque Reduction Neutralization Assay","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":true,"active":true,"synonyms":[{"name":"PLAQUE REDUCTION NEUTRALIZATION ASSAY","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"CDISC"},{"name":"Plaque Reduction Neutralization Test","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"CDISC"},{"name":"PRNT","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"CDISC"},{"name":"Plaque Reduction Neutralization Assay","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Plaque Reduction Neutralization Test","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"PRNT","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Plaque Reduction Neutralization Assay","type":"Preferred_Name","typeCode":"P108"},{"name":"Plaque Reduction Neutralization Assay","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"SeroNet"}],"definitions":[{"definition":"A serological test that measures the ability of antibodies in specific concentrations of serum to prevent the formation of plaques in a cell monolayer when combined with a viral suspension.","code":"P97","type":"DEFINITION","source":"NCI"},{"definition":"An assay that is used to determine whether neutralizing antibodies that are present in a biological specimen can block viral infection/proliferation ex vivo, by counting the number of cytolytic plaques. This assay typically uses live virus.","code":"P325","type":"ALT_DEFINITION","source":"CDISC"}],"properties":[{"code":"P322","type":"Contributing_Source","value":"CDISC"},{"code":"P322","type":"Contributing_Source","value":"SeroNet"},{"code":"P208","type":"NCI_META_CUI","value":"CL519559"},{"code":"P106","type":"Semantic_Type","value":"Laboratory Procedure"}]}