{"code":"C16994","name":"Plasminogen","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":true,"active":true,"synonyms":[{"name":"Plasminogen","termType":"DN","type":"FULL_SYN","typeCode":"P90","source":"CTRP"},{"name":"EC 3.4.21.7","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Fibrinase Precursor","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Fibrinolysin Precursor","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Plasmin Precursor","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Plasminogen","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"PLG","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"PLMN","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Thrombolysin Precursor","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Plasminogen","type":"Display_Name","typeCode":"P107"},{"name":"Plasminogen","type":"Preferred_Name","typeCode":"P108"}],"definitions":[{"definition":"Plasminogen (810 aa, ~91 kDa) is encoded by the human PLG gene. This protein is involved in fibrinolysis, platelet activation and tissue remodeling.","code":"P97","type":"DEFINITION","source":"NCI"}],"properties":[{"code":"P322","type":"Contributing_Source","value":"CTRP"},{"code":"P98","type":"DesignNote","value":"Plasminogen conversion to the enzymatically active plasmin is mediated by plasminogen activator proteins and is dependent on binding to clots or cell surfaces."},{"code":"P366","type":"Legacy Concept Name","value":"Plasminogen"},{"type":"Logical_Definition","value":"true"},{"code":"P100","type":"OMIM_Number","value":"173350"},{"code":"P106","type":"Semantic_Type","value":"Amino Acid, Peptide, or Protein"},{"code":"P106","type":"Semantic_Type","value":"Enzyme"},{"code":"P93","type":"Swiss_Prot","value":"P00747"},{"code":"P207","type":"UMLS_CUI","value":"C0032140"}]}