{"code":"C16790","name":"Mixed Lymphocyte Reaction Test","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":true,"active":true,"synonyms":[{"name":"Mixed Leukocyte Reaction","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"CDISC"},{"name":"Mixed Lymphocyte Reaction","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"CDISC","code":"SDTM-LBTEST"},{"name":"Mixed Lymphocyte Reaction","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"CDISC"},{"name":"MLR","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"CDISC","code":"SDTM-LBTESTCD"},{"name":"Mixed Lymphocyte Culture","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Mixed Lymphocyte Reaction Test","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Mixed T Cells, B Cells","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Mixed Lymphocyte Reaction Test","type":"Preferred_Name","typeCode":"P108"}],"definitions":[{"definition":"A measurement of the histocompatibility at the HL-A locus between two populations of lymphocytes taken from two separate individuals.","code":"P325","type":"ALT_DEFINITION","source":"CDISC"},{"definition":"An assay that measures the proliferative response of lymphocytes from one individual when they are exposed to inactivated lymphocytes from another individual. The reaction can be performed on lymphocytes from the same individual (auto-MLR), from different individuals of the same species (allo-MLR), or individuals from different species (xeno-MLR). It is used to evaluate the potential for graft-versus-host or host-versus-graft reactions during transplantation procedures involving mismatched tissue types or individuals.","code":"P97","type":"DEFINITION","source":"NCI"}],"properties":[{"code":"P322","type":"Contributing_Source","value":"CDISC"},{"code":"P366","type":"Legacy Concept Name","value":"Mixed_Lymphocyte_Reaction_Test"},{"code":"P106","type":"Semantic_Type","value":"Laboratory Procedure"},{"code":"P207","type":"UMLS_CUI","value":"C0023509"}]}