{"code":"C147535","name":"Interleukin-23","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":true,"active":true,"synonyms":[{"name":"Interleukin-23","termType":"DN","type":"FULL_SYN","typeCode":"P90","source":"CTRP"},{"name":"IL-23","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"IL23","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Interleukin 23","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Interleukin-23","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Interleukin-23","type":"Display_Name","typeCode":"P107"},{"name":"Interleukin-23","type":"Preferred_Name","typeCode":"P108"}],"definitions":[{"definition":"A heterodimeric cytokine composed of interleukin-12 subunit beta and interleukin-23 subunit alpha. This complex binds to the interleukin-23 receptor complex, which activates the JAK-STAT signaling pathway and modulates the proliferation, differentiation and effector functions of T-lymphocytes, natural killer cells and some myeloid lineage cells.","code":"P97","type":"DEFINITION","source":"NCI"}],"properties":[{"code":"P322","type":"Contributing_Source","value":"CTRP"},{"code":"P208","type":"NCI_META_CUI","value":"CL546020"},{"code":"P106","type":"Semantic_Type","value":"Amino Acid, Peptide, or Protein"}]}