{"code":"C126958","name":"Complement C2","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":true,"active":true,"synonyms":[{"name":"Complement C2","termType":"DN","type":"FULL_SYN","typeCode":"P90","source":"CTRP"},{"name":"C2","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"C3/C5 Convertase","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Complement C2","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Complement Component 2","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"EC 3.4.21.43","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Complement C2","type":"Display_Name","typeCode":"P107"},{"name":"Complement C2","type":"Preferred_Name","typeCode":"P108"}],"definitions":[{"definition":"Complement C2 (752 aa, ~83 kDa) is encoded by the human C2 gene. This protein is involved in post-translational protein processing and complement activity.","code":"P97","type":"DEFINITION","source":"NCI"}],"properties":[{"code":"P322","type":"Contributing_Source","value":"CTRP"},{"code":"P98","type":"DesignNote","value":"Complement C2 is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a is a serine proteainase that combines with complement factor C4b to form the C3 or C5 convertase. (UniProt)"},{"type":"Logical_Definition","value":"true"},{"code":"P208","type":"NCI_META_CUI","value":"CL1647978"},{"code":"P100","type":"OMIM_Number","value":"613927"},{"code":"P106","type":"Semantic_Type","value":"Amino Acid, Peptide, or Protein"},{"code":"P106","type":"Semantic_Type","value":"Enzyme"},{"code":"P93","type":"Swiss_Prot","value":"P06681"}]}