{"code":"C121324","name":"Anti-Smith Antibody","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":true,"active":true,"synonyms":[{"name":"Anti-Smith Antibody","termType":"DN","type":"FULL_SYN","typeCode":"P90","source":"CTRP"},{"name":"Anti-Sm Antibody","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Anti-Sm-RNP Antibody","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Anti-Sm/RNP Antibody","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Anti-Smith Antibody","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Anti-Sm Antibody","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NICHD"},{"name":"Anti-Smith Antibody","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NICHD"},{"name":"Anti-Smith Antibody","type":"Display_Name","typeCode":"P107"},{"name":"Anti-Smith Antibody","type":"Preferred_Name","typeCode":"P108"}],"definitions":[{"definition":"An antinuclear antibody directed against small nuclear ribonucleoproteins (snRNPs), that is highly specific, but has poor sensitivity for systemic lupus erythematosus (SLE). Presence of anti-Sm antibodies are associated with central nervous system, kidney, lung and cardiac involvement in SLE, but are not indicative of disease activity.","code":"P325","type":"ALT_DEFINITION","source":"NICHD"},{"definition":"An antinuclear antibody directed against small nuclear ribonucleoproteins (snRNPs), that is highly specific, but has poor sensitivity for systemic lupus erythematosus (SLE). Presence of anti-Sm antibodies are associated with central nervous system, kidney, lung and cardiac involvement in SLE, but are not indicative of disease activity.","code":"P97","type":"DEFINITION","source":"NCI"}],"properties":[{"code":"P322","type":"Contributing_Source","value":"CTRP"},{"code":"P322","type":"Contributing_Source","value":"NICHD"},{"code":"P106","type":"Semantic_Type","value":"Amino Acid, Peptide, or Protein"},{"code":"P106","type":"Semantic_Type","value":"Immunologic Factor"},{"code":"P207","type":"UMLS_CUI","value":"C0587072"}]}