{"code":"C114300","name":"Carboxyhemoglobin","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":true,"active":true,"synonyms":[{"name":"Carboxyhemoglobin","termType":"DN","type":"FULL_SYN","typeCode":"P90","source":"CTRP"},{"name":"Carboxyhemoglobin","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"COHb","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Carboxyhemoglobin","type":"Display_Name","typeCode":"P107"},{"name":"Carboxyhemoglobin","type":"Preferred_Name","typeCode":"P108"}],"definitions":[{"definition":"Hemoglobin where the heme group has formed a stable complex with carbon monoxide (CO). This complex is produced after CO has been inhaled or as a byproduct of hemoglobin, protoporphyrin or dichloromethane catabolism. The heme-CO complex is approximately 200 times more stable than heme-oxygen complexes. Thus, high levels of carboxyhemoglobin in the circulation can lead to tissue hypoxia and death.","code":"P97","type":"DEFINITION","source":"NCI"}],"properties":[{"code":"P322","type":"Contributing_Source","value":"CTRP"},{"code":"P98","type":"DesignNote","value":"Tobacco smokers have a higher physiologic percentage of COHb than non-smokers."},{"code":"P106","type":"Semantic_Type","value":"Amino Acid, Peptide, or Protein"},{"code":"P207","type":"UMLS_CUI","value":"C0007061"}]}