{"code":"C113245","name":"Creatine Kinase","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":false,"active":true,"synonyms":[{"name":"Creatine Kinase","termType":"DN","type":"FULL_SYN","typeCode":"P90","source":"CTRP"},{"name":"Adenosine Triphosphate-Creatine Transphosphorylase","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"ATP:Creatine N-Phosphotransferase","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"ATP:Creatine Phosphotransferase","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"CK","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"CPK","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Creatine Kinase","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Creatine Phosphokinase","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Creatine Phosphotransferase","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Phosphocreatine Kinase","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Creatine Kinase","type":"Display_Name","typeCode":"P107"},{"name":"Creatine Kinase","type":"Preferred_Name","typeCode":"P108"}],"definitions":[{"definition":"An enzyme complex that can reversibly convert ATP and creatine to phosphocreatine and ADP. Cytosolic creatine kinases are comprised of homodimers or heterodimers of creatine kinase B-type protein and creatine kinase M-type protein. Mitochondrial creatine kinases are octomers comprised of either four homodimers of creatine kinase U-type, mitochondrial protein or four creatine kinase S-type, mitochondrial protein homodimers.","code":"P97","type":"DEFINITION","source":"NCI"}],"properties":[{"code":"P322","type":"Contributing_Source","value":"CTRP"},{"code":"P106","type":"Semantic_Type","value":"Amino Acid, Peptide, or Protein"},{"code":"P106","type":"Semantic_Type","value":"Enzyme"},{"code":"P207","type":"UMLS_CUI","value":"C0010287"}]}