{"code":"C106048","name":"Chromatin Immunoprecipitation","terminology":"ncit","version":"26.09d","conceptStatus":"DEFAULT","leaf":false,"active":true,"synonyms":[{"name":"ChIP","termType":"SY","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Chromatin Immunoprecipitation","termType":"PT","type":"FULL_SYN","typeCode":"P90","source":"NCI"},{"name":"Chromatin Immunoprecipitation","type":"Preferred_Name","typeCode":"P108"}],"definitions":[{"definition":"A technique that utilizes immunoprecipitation to find protein-DNA interactions in a biological sample. First, the sample is treated causing the formation of protein-chromatin crosslinks. Then, the sample is sheared to separate individual protein-DNA complexes. Finally, an antibody directed against a protein of interest is applied and the protein-DNA complexes are immunoprecipitated.","code":"P97","type":"DEFINITION","source":"NCI"}],"properties":[{"code":"P106","type":"Semantic_Type","value":"Molecular Biology Research Technique"},{"code":"P207","type":"UMLS_CUI","value":"C1328856"}]}